What does HOMA-IR mean on the Premium screen?

HOMA-IR is a score worked out from your glucose and insulin levels that estimates insulin resistance, where your body needs more insulin to control blood sugar. It is most meaningful on a fasting sample and is read alongside HbA1c and your other results.

Should I keep taking my supplements before the test?

Keep taking prescribed medicines. If you take a high dose of biotin (5mg or more a day), stop it for a week before your test if it is safe to do so. Tell us about any other supplements, as vitamin B12 in particular can make your result look normal without fully treating a deficiency.

Why does the Premium screen have male and female versions?

Some hormone tests differ: the women’s version includes progesterone and the free androgen index, and the men’s version includes free testosterone and cortisol. We use the right version for you.

Premium Advanced Nutrition & Hormones Blood Test at Jace Medical

Health screens

Private blood test

Premium Advanced Nutrition & Hormones Blood Test

A premium screen combining advanced nutrition and hormone markers. Contact us for the current price.

77 biomarkers
Fasting recommended

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We confirm your appointment and any preparation, such as fasting, before you attend.

What’s included

77 biomarkers in this test.

Some markers differ for men and women. The clinic team selects the correct version when your sample is ordered.

Fasting recommended before this test

Heart & cholesterol12

Cholesterol and other fats in the blood that are linked to heart health.

Apolipoprotein A-I
Apolipoprotein B
Apolipoprotein B / A-I Ratio
Apolipoprotein E
HDL
Homocysteine
LDL
Lipoprotein (a)
Small LDL Cholesterol
Total Cholesterol
Total Cholesterol / HDL Cholesterol Ratio
Triglycerides

Blood sugar & diabetes5

How your body manages sugar, including your average level over recent months.

C-peptide
Glucose
Insulin
HbA1c
HOMA-IR

Liver7

Enzymes and proteins that show how well your liver is working.

Alanine Aminotransferase (ALT)
Albumin
Alkaline Phosphatase (ALP)
Aspartate Aminotransferase (AST)
Gamma-Glutamyltransferase (GGT)
Total Bilirubin
FIB-4 (Calculation)

Kidneys6

How well your kidneys filter waste from your blood.

Creatinine
Cystatin C
Estimated Glomerular Filtration Rate (eGFR)
Microalbumin / Creatinine Ratio
Urea
Urinalysis

Body salts & minerals8

Electrolytes and minerals that help your nerves, muscles and heart work properly.

Calcium (adjusted)
Chloride
Copper
Magnesium
Phosphate
Potassium
Sodium
Zinc

Iron & anaemia5

Your iron levels and stores, a common cause of tiredness when low.

Ferritin
Iron
Total Iron Binding Capacity (TIBC)
Transferrin
Transferrin Saturation

Vitamins5

Key vitamins for energy, nerves, bones and healthy blood.

Folic acid
Vitamin B12
Vitamin D
Active B12
Red Cell Folate

Blood count1

Your red cells, white cells and platelets.

Full Blood Count

Thyroid5

How well your thyroid is working, and antibodies linked to thyroid conditions.

Anti-Thyroglobulin Antibody (Anti-Tg)
Anti-Thyroid Peroxidase Antibody (Anti-TPO)
Free Thyroxine (FT4)
Free Tri-iodothyronine (FT3)
Thyroid Stimulating Hormone (TSH)

Hormones & fertility11

Reproductive, stress and adrenal hormones.

Dehydroepiandrosterone Sulphate (DHEAs)
Follicle Stimulating Hormone
Free Androgen Index
Luteinising Hormone
Oestradiol
Progesterone
Prolactin
Sex Hormone Binding Globulin (SHBG)
Testosterone
Cortisol
Free Testosterone

Inflammation & immunity9

Signs of inflammation in the body and how your immune system is working.

Antistreptolysin O (ASO)
Complement Component 4 (C4)
C-Reactive Protein (CRP)
High Sensitivity C-Reactive Protein (hsCRP)
Immunoglobulin A (IgA)
Immunoglobulin E (IgE)
Immunoglobulin G (IgG)
Immunoglobulin M (IgM)
Rheumatoid Factor (RF)

Muscle & bone1

Markers of muscle damage and the hormone that controls calcium in your bones.

Parathyroid Hormone (PTH)

Digestion & pancreas2

Pancreas function, coeliac disease screening, gut inflammation and H. pylori, a common stomach infection.

Lipase
Pancreatic Amylase

About this test

Is the Premium Advanced Nutrition & Hormones Blood Test right for you?

Who it’s for

You want a detailed look at your nutrition, including several measures of vitamin B12 and folate, iron, vitamin D, zinc, copper and magnesium.
You have symptoms that may be hormonal, such as low energy, low sex drive, irregular periods or menopause symptoms, and want hormones checked alongside your general health.
You want to understand your heart and metabolic health in depth, including insulin resistance and lipoprotein(a).
You follow a restricted diet, or have a condition that affects how you absorb nutrients, and want a wide nutritional check.

What it can show

Nutrition markers include total and active vitamin B12, folate and red cell folate, homocysteine, a full iron profile, vitamin D, zinc, copper and magnesium. NICE says either total or active B12 can be used as the first test for B12 deficiency.
Hormone markers include thyroid tests with antibodies, FSH, LH, oestradiol, prolactin, testosterone, SHBG and DHEA sulphate (an adrenal hormone), with progesterone for women and cortisol for men.
Heart and metabolic markers include a full cholesterol profile with apolipoproteins, small LDL and lipoprotein(a), plus glucose, HbA1c, insulin, C-peptide and HOMA-IR, an estimate of insulin resistance worked out from glucose and insulin.
Liver tests with a FIB-4 score, kidney tests with cystatin C and a urine albumin:creatinine ratio, pancreas enzymes, and PTH, adjusted calcium and phosphate cover organ and bone health.
Inflammation and immune markers (CRP, hsCRP, immunoglobulins, complement C4, rheumatoid factor and ASO) can show signs of inflammation or immune activity that may need a closer look.

What it can’t tell you

Vitamin B12 supplements can raise total and active B12 results without fully treating a deficiency, and the combined contraceptive pill can lower total B12. Some people have symptoms of deficiency with normal levels.
Hormone results vary with the time of day, the menstrual cycle, hormonal contraception or HRT, and stress. A single cortisol result has limited value and is best taken at about 9am.
Insulin and HOMA-IR are easiest to interpret on a fasting sample, so results after eating may be less reliable.
One result is a snapshot, and borderline results usually need repeating before any decision is made.
Results need to be interpreted alongside your symptoms. Decisions about diagnosis, supplements or hormone treatment are made with your GP, specialist or prescriber.

Before your test

The lab does not require a fasting sample, but we recommend one: insulin, glucose and HOMA-IR are easier to interpret when you have not eaten. If you can, have nothing except water for 8 to 12 hours beforehand, and tell us when you last ate.
Book a morning appointment, ideally around 9am, as testosterone and cortisol are highest in the morning. Women should tell us the first day of their last period and any hormonal contraception or HRT.
Biotin (vitamin B7), found in some hair, skin and nail supplements, can affect some hormone and thyroid results. Tell us if you take it, and if you take a high dose (5mg or more a day), stop it for a week before your test if it is safe to do so. Tell us about any other supplements you take, especially vitamin B12.
Do not eat meat in the 12 hours before your test, as NICE advises for kidney function (eGFR) tests.

Your results

Usually within a couple of working days. We email your results once a doctor has reviewed them.

How it works

From booking to results in three steps.

Step 1
Request your test
Send a booking request online or call us. We confirm your clinic, appointment time and any preparation.
Step 2
Visit the clinic
A short appointment for professional sample collection at Greysteel or Letterkenny. No GP referral needed.
Step 3
Receive your results
Usually within a couple of working days, emailed to you once a doctor has reviewed them.

Common questions

Questions about this test.

Total B12 measures all the vitamin B12 in your blood, while active B12 measures a smaller part of it called holotranscobalamin. NICE says either can be used as the first test for suspected B12 deficiency, and this screen includes both.