Does the Advanced Screen include cancer markers?

Yes. Men have a PSA test and women a CA 125 test. These are not cancer screening tests on their own: raised results often have other causes and normal results do not rule cancer out, so a doctor reads them alongside your other results.

What is lipoprotein(a)?

Lipoprotein(a), or Lp(a), is a cholesterol-carrying particle similar to LDL. Your level is mainly set by your genes, and HEART UK says high levels are linked with heart disease and stroke at a young age.

Does Advanced Screen Plus test for food allergies or intolerances?

It includes total IgE and an IgE allergy test, which can show whether your immune system is sensitised to allergens; this does not always mean you are allergic. It is not a food intolerance (IgG) test, which Allergy UK does not recommend, and a severe reaction such as swelling of the lips or throat or difficulty breathing needs urgent care: call 999.

Advanced Screen Blood Test at Jace Medical

Health screens

Private blood test

Advanced Screen Blood Test

A detailed health screen covering heart, metabolic, hormonal and nutritional markers, or our most comprehensive screen with Plus.

50 biomarkers
Fasting required

Choose your panel

Advanced Screen50 biomarkers£219Advanced Screen Plus89 biomarkers£369

Advanced Screen

£219Includes sample collection

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We confirm your appointment and any preparation, such as fasting, before you attend.

What’s included

50 biomarkers in Advanced Screen.

Some markers differ for men and women. The clinic team selects the correct version when your sample is ordered.

Fasting required before this test

Heart & cholesterol11

Cholesterol and other fats in the blood that are linked to heart health.

Apolipoprotein A-I
Apolipoprotein B
Apolipoprotein B / A-I Ratio
Apolipoprotein E
HDL
LDL
Lipoprotein (a)
Small LDL Cholesterol
Total Cholesterol
Total Cholesterol / HDL Cholesterol Ratio
Triglycerides

Blood sugar & diabetes5

How your body manages sugar, including your average level over recent months.

Adiponectin
C-peptide
Glucose
Insulin
HbA1c

Liver6

Enzymes and proteins that show how well your liver is working.

Alanine Aminotransferase (ALT)
Albumin
Alkaline Phosphatase (ALP)
Aspartate Aminotransferase (AST)
Gamma-Glutamyltransferase (GGT)
Total Bilirubin

Kidneys6

How well your kidneys filter waste from your blood.

Creatinine
Cystatin C
Estimated Glomerular Filtration Rate (eGFR)
Urea
Uric Acid
Urinalysis

Body salts & minerals6

Electrolytes and minerals that help your nerves, muscles and heart work properly.

Calcium (adjusted)
Chloride
Magnesium
Phosphate
Potassium
Sodium

Iron & anaemia5

Your iron levels and stores, a common cause of tiredness when low.

Ferritin
Iron
Total Iron Binding Capacity (TIBC)
Transferrin
Transferrin Saturation

Vitamins1

Key vitamins for energy, nerves, bones and healthy blood.

Vitamin D

Blood count1

Your red cells, white cells and platelets.

Full Blood Count

Thyroid5

How well your thyroid is working, and antibodies linked to thyroid conditions.

Anti-Thyroglobulin Antibody (Anti-Tg)
Anti-Thyroid Peroxidase Antibody (Anti-TPO)
Free Thyroxine (FT4)
Free Tri-iodothyronine (FT3)
Thyroid Stimulating Hormone (TSH)

Inflammation & immunity2

Signs of inflammation in the body and how your immune system is working.

C-Reactive Protein (CRP)
High Sensitivity C-Reactive Protein (hsCRP)

Cancer markers2

Markers doctors use alongside other checks. A raised result does not mean cancer, and a normal result does not rule it out.

Cancer Antigen 125 (CA 125)
Total Prostate Specific Antigen (TPSA)

About this test

Is the Advanced Screen Blood Test right for you?

Who it’s for

You want a detailed picture of your heart and metabolic health that goes beyond a standard cholesterol test.
Heart disease or stroke at a young age runs in your family and you want markers such as lipoprotein(a) checked.
You have ongoing symptoms such as tiredness and want thyroid, iron, kidney and liver markers checked together.
You want a very wide panel that also covers vitamins, hormones, gut and immune markers (Advanced Screen Plus).

What it can show

Heart markers go beyond a standard cholesterol test. As well as total, HDL and LDL cholesterol and triglycerides, it measures apolipoproteins, small LDL and lipoprotein(a), a mainly inherited cholesterol particle that is not usually measured in a routine cholesterol test.
Glucose, HbA1c, insulin, C-peptide and adiponectin can help show how your body is handling sugar, including signs of insulin resistance. Uric acid can be raised in gout.
Liver tests, kidney tests (creatinine, eGFR, cystatin C and a urine test), a full blood count, iron studies, ferritin, magnesium, adjusted calcium and vitamin D give a broad view of organ function, anaemia and nutrition. Thyroid tests (TSH, free T4, free T3 and antibodies) show how your thyroid is working.
Men also have a PSA test and women a CA 125 test. These are tumour markers, which can be raised by many conditions other than cancer and are not screening tests on their own.
Advanced Screen Plus adds vitamin B12, folate, PTH, creatine kinase (a muscle enzyme), pancreas enzymes, sex hormones, immune proteins (immunoglobulins, complement, rheumatoid factor and ASO), an H. pylori antibody test, a coeliac antibody test (tTG IgA) and an IgE allergy test. These can help look into symptoms such as tiredness, joint pain, indigestion or gut problems. It also reports total antioxidant status, which is not used in NHS or NICE guidance and is background information only.

What it can’t tell you

PSA and CA 125 are not screening tests for cancer on their own. Raised levels have many non-cancer causes, such as a urine infection for PSA or endometriosis, fibroids or pregnancy for CA 125, and a normal result does not rule cancer out.
PSA testing is an informed choice. It can help pick up prostate cancer early, but it can also miss cancer or lead to tests and treatment you may not need, which is why routine PSA screening is not offered in the UK or Ireland for most men.
Some Plus results need careful interpretation. A positive IgE allergy test shows sensitisation, not necessarily an allergy, the coeliac test is only accurate if you are eating gluten, and NICE recommends a breath test, not a blood test, to check whether H. pylori treatment has worked.
Several results vary from day to day. Hormones change with the time of day and menstrual cycle, vitamin D with the season, uric acid can be lower during a gout flare and creatine kinase rises after hard exercise, so some results may need repeating.
Results need to be interpreted alongside your symptoms and medical history. Diagnosis and treatment of any condition are made with your GP or specialist.

Before your test

This test needs a fasting sample. Have nothing to eat or drink except water for 8 to 12 hours beforehand, so an overnight fast and a morning appointment work best. That means no tea, coffee (including black coffee) or fizzy drinks.
Biotin (vitamin B7), found in some hair, skin and nail supplements, can affect some hormone and thyroid results. Tell us if you take it, and if you take a high dose (5mg or more a day), stop it for a week before your test if it is safe to do so. Keep taking other medicines unless your doctor tells you otherwise, tell us about any vitamin B12 supplements, and if you have diabetes, speak to your doctor before you fast.
Men: for 48 hours before your test, avoid ejaculation and vigorous exercise, including cycling, as these can raise PSA. If you have had a urine infection, wait 4 to 6 weeks after it has cleared before testing.
For Plus, avoid strenuous exercise beforehand, as it raises creatine kinase, and keep eating gluten in more than one meal every day for at least 6 weeks before the coeliac test. Women having Plus should tell us the first day of their last period and any hormonal contraception or HRT.

Your results

Usually within a couple of working days. We email your results once a doctor has reviewed them.

How it works

From booking to results in three steps.

Step 1
Request your test
Send a booking request online or call us. We confirm your clinic, appointment time and any preparation.
Step 2
Visit the clinic
A short appointment for professional sample collection at Greysteel or Letterkenny. No GP referral needed.
Step 3
Receive your results
Usually within a couple of working days, emailed to you once a doctor has reviewed them.

Common questions

Questions about this test.

Plus adds vitamin B12 and folate, PTH, creatine kinase, pancreas enzymes, sex hormones, immune markers, and tests for H. pylori antibodies, coeliac disease antibodies and IgE allergy. It suits people who want to look into specific symptoms as well as their general health.